New blood pressure drug helps people with uncontrolled hypertension in trial

Published on April 22, 2025

This recent development in the field of hypertension treatment is indeed promising, as it offers hope for those with uncontrolled blood pressure who have not found relief through conventional methods. The Phase 2b clinical trial results show a significant decrease in systolic blood pressure when lorundrostat was combined with existing hypertension drugs, which could potentially improve the overall management of this condition.

The study's lead author, Dr. Luke Laffin, highlights the importance of better controlling blood pressure levels in the United States, where only a small percentage of those diagnosed with hypertension have their condition under control. This is concerning given that uncontrolled hypertension increases the risk of heart attacks, strokes, heart failure, and kidney failure.

The fact that lorundrostat is part of a class called aldosterone synthase inhibitors suggests it may work differently from other medications currently available for hypertension treatment. This could be particularly beneficial for those who have not seen success with existing therapies. The drug's potential to improve blood pressure control rates, which are currently at 60%-70%, is a significant step forward in addressing the unmet needs of millions of patients worldwide.

However, it is essential to note that while these results are encouraging, further research and clinical trials will be necessary to fully understand lorundrostat's long-term effects and potential side effects. Additionally, as with any new medication, its accessibility and affordability should also be considered in order to ensure equitable treatment options for all patients who may benefit from this innovative approach to hypertension management.

[Original Article](https://www.nbcnews.com/health/heart-health/new-blood-pressure-drug-helps-people-uncontrolled-hypertension-trial-rcna198443) #blood #pressure [Visit GhostAI](https://ghostai.pro/)

[Join our Discord](https://discord.com/invite/zgKZUJ6V8z)